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1

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

Swift, J., Ivanovska, I. L., Buxboim, A., Harada, T., Dingal, P. C. D. P., Pinter, J., Pajerowski, J. D., Spinler, K. R., Shin, J.-W., Tewari, M., Rehfeldt, F., Speicher, D. W., Discher, D. E.

Journal:

Year:

2013

Language:

english

File:

PDF, 3.76 MB

english, 2013

2

Fractal heterogeneity in minimal matrix models of scars modulates stiff-niche stem-cell responses via nuclear exit of a mechanorepressor

Dingal, P. C. Dave P., Bradshaw, Andrew M., Cho, Sangkyun, Raab, Matthew, Buxboim, Amnon, Swift, Joe, Discher, Dennis E.

Journal:

Nature Materials

Year:

2015

Language:

english

File:

PDF, 5.87 MB

english, 2015

3

Fractal Heterogeneity in Minimal Matrix Models of Scars Modulates Stiff-Niche Stem-Cell Responses Via Nuclear Exit of a Mechanorepressor

Dingal, P.C. Dave P., Xia, Yuntao, Discher, Dennis E.

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 42 KB

english, 2016

4

Manipulating the mechanics of extracellular matrix to study effects on the nucleus and its structure

Xia, Yuntao, Cho, Sangkyun, Vashisth, Manasvita, Ivanovska, Irena L., Dingal, P.C. Dave P., Discher, Dennis E.

Journal:

Year:

2018

Language:

english

File:

PDF, 926 KB

english, 2018

5

The application of Taguchi’s method in the experimental investigation of the laser sintering process

S. Dingal, T. R. Pradhan, J. K. Sarin Sundar, A. Roy Choudhury, S. K. Roy

Journal:

The International Journal of Advanced Manufacturing Technology

Year:

2008

Language:

english

File:

PDF, 306 KB

english, 2008

6

Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain

Raab, M., Swift, J., P. Dingal, P. C. D., Shah, P., Shin, J.-W., Discher, D. E.

Journal:

The Journal of Cell Biology

Year:

2012

Language:

english

File:

PDF, 2.99 MB

english, 2012

7

Contractile Forces Sustain and Polarize Hematopoiesis from Stem and Progenitor Cells

Shin, Jae-Won, Buxboim, Amnon, Spinler, Kyle R., Swift, Joe, Christian, David A., Hunter, Christopher A., Léon, Catherine, Gachet, Christian, Dingal, P.C. Dave P., Ivanovska, Irena L., Rehfeldt, Flori

Journal:

Year:

2014

Language:

english

File:

PDF, 2.89 MB

english, 2014

8

Material control of stem cell differentiation: challenges in nano-characterization

Dingal, PC Dave P, Discher, Dennis E

Journal:

Current Opinion in Biotechnology

Year:

2014

Language:

english

File:

PDF, 226 KB

english, 2014

9

Combining insoluble and soluble factors to steer stem cell fate

Dingal, P. C. Dave P., Discher, Dennis E.

Journal:

Nature Materials

Year:

2014

Language:

english

File:

PDF, 1.25 MB

english, 2014

10

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival

Harada, T., Swift, J., Irianto, J., Shin, J.-W., Spinler, K. R., Athirasala, A., Diegmiller, R., Dingal, P. C. D. P., Ivanovska, I. L., Discher, D. E.

Journal:

The Journal of Cell Biology

Year:

2014

Language:

english

File:

PDF, 2.96 MB

english, 2014

11

Fibrillar Collagen is Equivalent to Stiff Matrix in Driving Marrow Stromal Cell Differentiation into a Matrix-Deficient, Myofibroblastic-Like Phenotype

Dingal, P.C. Dave P., Raab, Matthew, Shah, Palak, Shin, Jae-Won, Discher, Dennis

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 76 KB

english, 2013

12

Stress Sensitivity and Mechanotransduction during Heart Development

Majkut, Stephanie, Dingal, P.C. Dave P., Discher, Dennis E.

Journal:

Current Biology

Year:

2014

Language:

english

File:

PDF, 353 KB

english, 2014

13

Matrix Elasticity Regulates Lamin-A,C Phosphorylation and Turnover with Feedback to Actomyosin

Buxboim, Amnon, Swift, Joe, Irianto, Jerome, Spinler, Kyle R., Dingal, P.C. Dave P., Athirasala, Avathamsa, Kao, Yun-Ruei C., Cho, Sangkyun, Harada, Takamasa, Shin, Jae-Won, Discher, Dennis E.

Journal:

Current Biology

Year:

2014

Language:

english

File:

PDF, 1.34 MB

english, 2014

14

Systems Mechanobiology: Tension-Inhibited Protein Turnover Is Sufficient to Physically Control Gene Circuits

Dingal, P.C. Dave P., Discher, Dennis E.

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 687 KB

english, 2014

15

Simple insoluble cues specify stem cell differentiation: Fig. 1.

Dingal, P. C. Dave P., Wells, Rebecca G., Discher, Dennis E.

Journal:

Proceedings of the National Academy of Sciences

Year:

2014

Language:

english

File:

PDF, 646 KB

english, 2014

16

Systems Mechano-Biology: Tension-Inhibited Protein Turnover is Sufficient to Physically Control Gene Circuits

Dingal, P.C. Dave P., Discher, Dennis E.

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 59 KB

english, 2015

17

[IEEE 2014 40th Annual Northeast Bioengineering Conference (NEBEC) - Boston, MA, USA (2014.4.25-2014.4.27)] 2014 40th Annual Northeast Bioengineering Conference (NEBEC) - Nuclear lamin stiffness is a barrier to 3D-migration, but softness can limit survival

Harada, Takamasa, Swift, Joe, Irianto, Jerome, Shin, Jae-Won, Spinler, Kyle R., Athirasala, Avathamsa, Diegmiller, Rocky, Dingal, P. C. Dave P., Ivanovska, Irena L., Discher, Dennis E.

Year:

2014

Language:

english

File:

PDF, 1.86 MB

english, 2014

18

Cross-Linked Matrix Rigidity and Soluble Factors Induce Differentiation via Distinct but Overlapping Pathways

Ivanovska, Irena L., Swift, Joe, Spinler, Kyle, Dingal, P.C. Dave P., Discher, Dennis E.

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 54 KB

english, 2015

19

Matrix and Soluble Factor Pathways to Lineage Specification

Ivanovska, Irena L., Swift, Joe, Spinler, Kyle, Dingal, Dave, Discher, Dennis E.

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 40 KB

english, 2016

20

SIRPA-Inhibited, Marrow-Derived Macrophages Engorge, Accumulate, and Differentiate in Antibody-Targeted Regression of Solid Tumors

Alvey, Cory M., Spinler, Kyle R., Irianto, Jerome, Pfeifer, Charlotte R., Hayes, Brandon, Xia, Yuntao, Cho, Sangkyun, Dingal, P.C.P. Dave, Hsu, Jake, Smith, Lucas, Tewari, Manu, Discher, Dennis E.

Journal:

Current Biology

Year:

2017

Language:

english

File:

PDF, 4.87 MB

english, 2017

21

Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system

Kipniss, Nathan H., Dingal, P. C. Dave P., Abbott, Timothy R., Gao, Yuchen, Wang, Haifeng, Dominguez, Antonia A., Labanieh, Louai, Qi, Lei S.

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 874 KB

english, 2017